Mutational and Kinetic Analysis of APE1 Endoribonuclease Activity
نویسندگان
چکیده
منابع مشابه
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Endonucleolytic cleavage of the coding region determinant (CRD) of c-myc mRNA appears to play a critical role in regulating c-myc mRNA turnover. Using (32)P-labeled c-myc CRD RNA as substrate, we have purified and identified two endoribonucleases from rat liver polysomes that are capable of cleaving the transcript in vitro. A 17-kDa enzyme was identified as RNase1. Apurinic/apyrimidinic (AP) DN...
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ژورنال
عنوان ژورنال: Molecular Biology
سال: 2021
ISSN: 0026-8933,1608-3245
DOI: 10.1134/s0026893321020102